Registry of Work

Mucosal vaccine formulations for targeted therapy of HPV cancers

Project Description

We obtained preliminary evidence for an alternate safer approach of HPV peptide vaccination using two adjuvants with superior capacity to enhance vaccine-mediated immunity and recognized for their safety in human clinical trials. This proposal will build on these encouraging data towards preclinical confirmation of the safety and efficacy of this vaccination along with understanding the underlying mechanisms for future implementation in human clinical testing against HPV+ cervical and oral cancers.

Project Type

Academic Research; vaccine research

Target Population

n/a

Related Cancers

Cervix Uteri, Head and Neck, Vagina

Project Lead

Sastry, Jagannadha

Contact Info

sastry@mdanderson.org

Website

https://www.cprit.state.tx.us/grants-funded/grants/rp180472

Funded Organization

The University of Texas M.D. Anderson Cancer Center

Collaborating Organizations

Funding Amount

$883,146

Funding Source

CPRIT

Counties

Award Date

2/21/2018

Start Date

n/a

End Date

n/a